No data are available in the peer reviewed scientific literature to document the potential effectiveness of the gene knockdown strategy in the treatment of alcoholism. F. (2013) BioSM: Metabolomics Tool for Identifying Endogenous Mammalian Biochemical Structures in Chemical Structure Space, J. For detailed information regarding reproductive toxicology, sponsors should refer to the document entitled, "Guideline for Industry, Detection of Toxicity to Reproduction for Medicinal Products."

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