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The patient has neuroleptic malignant syndrome (NMS) and likely has muscle rigidity, so give him dantrolene. Pharmacokinetics influences decisions over the route of administration. The hydrophilic carboxy-terminus accounts for its water soluble nature, whereas the hydrophobic amino terminus promotes its spontaneous and rapid interactions with phospholipid membranes. Prerequisite: Graduate standing in Pharmacology and Toxicology Program.
Pages: 328
Publisher: The MIT Press; 1 edition (August 16, 2002)
ISBN: B004NNUV4U
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