Anxiety, as a natural defence response, with a genetic basis (Marks, 1986), whose variation may be due to genetic defects or normal variation (Nesse & Williams, 1996), and an adaptive function, is obviously an evolutionary phenomenon. Cohler, Basia Carolyn Miller, and Harold Samuel Stone, (Cambridge: Cambridge University Press), 1988. Sagan himself presented a paper at that conference, in which he reports (pp. 45-6) the odds against a specific human genome being assembled by chance as 1 in 10^2,000,000,000 (in other words, the genome of a specific person, and not just any human).

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